Special Section: Aspects of Biotechnology

نویسندگان

  • Brendan J. McConkey
  • Vladimir Sobolev
  • Marvin Edelman
چکیده

Computer-based methods for predicting the structure of ligand–protein complexes or docking algorithms have application in both drug design and the elucidation of biochemical pathways. The number of solved structures of ligand–protein complexes now permits the testing and validation of docking algorithms, by comparison of predicted complexes with structures extracted from protein databases. This paper outlines the methodologies and compares their performance in predicting the structure of ligand– protein complexes.

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تاریخ انتشار 2002